Transdermal Diffusion

What is transdermal diffusion?
Instructions for use, explanations and advertising slogans from cosmetics
and pharmacology related to skin agents such as "penetrates deep into the skin"
or "penetrates into different skin layers" are well known. the
Description "Transdermal diffusion" means nothing else, just something
more professionally paraphrased, "transdermal" being "through the skin."
through” or “absorbed into the body through the skin”
and "diffusion" means the independent mixing, the passive
ongoing transport without having to do anything, mixing /
Balancing in cells, bodies... due to different concentrations /
concentration balance.

Significance and applications of transdermal diffusion
The great significance and importance of transdermal diffusion has been recognized in many fields, including cosmetics, and there are numerous
Investigations, studies and treatises on this in pharmacology
and medicine, but especially in relation to special, with active ingredients
fitted patches through which substances are introduced into the body,
E.g. nicotine patches, hormone patches etc. and unfortunately only very little in relation
on baths. It does, however, give out crucial details and clues
these treatises and studies sufficient to draw conclusions
to be able to In cosmetics, it is important to distinguish whether something should "only" make you beautiful by "surface treatment" with lipstick, make-up, etc., or whether it should also have an effect / change on and in the skin. If a beautification is to take place by something also or primarily having an effect / changing it for the better, then transdermal diffusion cannot be avoided in cosmetics either. The physical method of "microneedling" is often used by beauticians to transport the active ingredients deeper into the skin with the help of tiny needles. It is very controversial, especially in English-speaking countries, whether magnesium enters the body transdermally via baths in magnesium chloride, which is also somewhat confusingly referred to as magnesium oil, and if so, in what quantities.

What factors favor transdermal diffusion?
Even if it's not a pretty picture, it can be compared to one
Knife. If it's blunt and round at the tip, it won't penetrate the skin.
If, on the other hand, it is sharp and pointed at the tip, it penetrates the skin, is in
particularly the outer protective barrier of the skin, the horny layer or
the stratum corneum, to overcome or break through.

1. pH
In a figurative sense, this also applies to chemical substances and
physical conditions. If the substances are pH-neutral, i.e. at 7,
they will penetrate less than at acidic and basic pH values.
In order to promote transdermal diffusion, various
Promoter or enhancer substances used, which are often very acidic, eg
Alcohols, urea (urea), salicylic acid, etc. These substances make the skin
even more sour than she already is. Therefore, these substances should
skin products should be avoided in our opinion.
A small digression at this point:
There are different opinions on this. First the opinion that the skin of adults is often very acidic and therefore a good, normal one
Condition that needs to be maintained in order to protect the skin's protective barrier
support. It has been found, for example, that urea has the protective function
supports, makes the skin acidic, and then only very little
gets through, so transdermal diffusion to a minimum
is driven back.
The opposite view holds that small babies
still have a much higher pH value of the skin and the skin before
is also a huge detoxification organ in which excess acids are released
be conveyed to the outside, if the skin's environment is too acidic
But detoxification prevents it, the skin seals it off, so to speak, because it already
is too acidic and cannot tolerate more acid. Therefore one should
Treat skin with alkaline, thus detoxifying the skin and the body
is promoted and the acids arriving there are neutralized and the possibility is created to transport more and more acids out there.
port and neutralize. If the skin is really stressed / disturbed and the protective barrier is actually weakened as a result, it will show this, for example
by rash, irritation, sensitivity, acne, neurodermatitis /
atopic eczema, etc. Everyone can then quickly test for themselves what the skin
better repaired and more beautiful, acidic or basic
skin remedy.

From personal experiences and field reports we can do that for
answer us unequivocally: Definitely alkaline skin products... I love
unfortunately eat acid-producing foods such as sweets, cola, etc
I'm anything but ideal, unfortunately I don't invest a lot of time and energy
on the topic, apart from good herbal teas, but I am regarding alkaline baths
and body care quite consistently and diligently and are therefore very similar
much again, as I at least think and hope. I'm almost 60 now
years old and feeling good.
Back to the topic of transdermal diffusion and the factors that cause it
favor. pH we just had. So alkaline baths are ours
In our opinion and experience, they are significantly healthier enhancers/promoters of transdermal diffusion than acidic enhancers such as alcohols, urea, salicylic
acid or solvents such as DMSO. LA VAGUE baths are very alkaline, but still in a well-tolerated range.

2. water
Well hydrated/moist skin is more permeable than dry
Skin. There are artificial methods to increase skin moisture,
eg the use of the very popular hyaluronic acid, which helps retain water in the
binding skin. However, the simplest method is very simple
and simply: baths. After a period of time in the water, the skin becomes very
well hydrated and much more receptive to transdermal
Diffusion, which then runs up to five times faster than when the skin is in the
dry condition. Therefore, basic baths in general and
LA VAGUE baths in particular are an ideal method of promotion
of transdermal diffusion.

3. Temperature
A higher temperature also helps. That is also very much in bathrooms
easier to organize with warm to slightly hot bath water. in the
In summer, however, cold LA VAGUE baths are also a real blessing. There
LA VAGUE baths contain many substances that transdermal
Promote diffusion, they also work very well in cool/cold water.

4. Vegetable oils
In the specialist literature it says: lipid content and composition
improve transdermal diffusion. Especially pure and high-quality
Vegetable oils are particularly good and effective here. Alkaline bath salts very rarely contain even one high-quality vegetable oil. In
LA VAGUE Sels de Bain not only has 1 good vegetable oil, there are
a total of 9 very high quality and pure organic vegetable oils.

5. Concentration of active ingredients
The more concentrated the active ingredients are, the greater the concentration
gradient to the skin, the better the transdermal diffusion works. The ingredients in LA VAGUE Sels de Bain are in high concentrations
beforehand so that they can work optimally. But the concentrations are not
only high, but also consistent with each other, complement each other perfectly,
to achieve the best possible results. However, this does not always mean that higher amounts of LA VAGUE Sels de Bain per bath and thus higher concentrations of the ingredients are always better and more effective. There are skin types with particular sensitivity and situations, e.g. skin irritations, skin problems, be it acne, atopic eczema (neurodermatitis), etc., where it may be better to start carefully with lower concentrations in order to find out how the skin reacts before the dose/concentration can then be gradually increased.

6. Skin condition, skin health, skin region
With baths, overall transdermal diffusion is much greater than with pure
local application with a patch or with much more localized application
Applications with skin products. In the case of bathrooms, a much larger one
Skin surface exposed to the active ingredients and there are also the many
Skin areas more fully treated and included where the skin
is more permeable. On the one hand, there are the skin regions where a lot of hair grows, but also there where the skin is thinner, e.g. on the face, on the neck, in
the hollows of the knees, on the arms, but also where there are many sweat glands,
like hands and feet. This in no way speaks against local ones
Applications with skin products that can make sense for local
skin improvements. However, it is important to point out that
Bathrooms play a special role when it comes to the overall
improvement of skin and body. That still applies to LA VAGUE bathrooms
once in an increased form, because a lot has been optimized here, what you
not found anywhere else.

7. Molecular Sizes
Smaller molecules or ions penetrate the skin more easily than larger ones.
So-called “ionic solutions” are particularly well suited. So that are in water
meaning dissolved salts. This is very true of the situation at LA VAGUE bathrooms
vicinity. The many minerals and trace elements in LA VAGUE Sels de
Bain form ions in the water and are therefore in a form that is very
is well suited to penetrate deep into the skin and into the organism.

8. Frequency and Time
The more often LA VAGUE baths are used and the longer they last
individual baths last, the clearer the transdermal diffusion becomes
fail over time and the greater the effects of the
many active ingredients on the skin and body. The time factor can also
intensify by not using the substances in a LA VAGUE bath
be dried off, but left on the skin, e.g
easy to dry on the skin in warm temperatures in the bathroom
and/or in summer etc. or by blow-drying the skin.

In summary, it can be stated that the most important factors of the
particularly effective for transdermal diffusion in LA VAGUE baths
will. In the following we will explain why LA VAGUE
Baths not “only” activate transdermal diffusion, but from it
then there is also a special benefit.